Molecular Cancer Therapeutics: Strategies for Drug Discovery and Development George C. Prendergast (Lankenau Institute for Medical Research, Wynnewood, Pennsylvania, and Thomas Jefferson University, Jefferson Medical College, Philadelphia, Pennsylvania, USA)
This invaluable reference promotes understanding of steps involved in developing drug leads for industrial partnering and development. It provides an overview of the strategies for discovery and validation of drug target molecules, and discusses cell- and molecule-based drug screening strategies, as well as mouse models for cancer. Coverage also includes how to refine drug leads for suitability in clinical testing, the special issues of clinical testing of molecular-targeted drugs, and intellectual property concerns.