I. LABORATORY PRINCIPLES 1. Introduction to Clinical Chemistry and Evidence-Based Laboratory Medicine 2. Introduction to Principles of Laboratory Analyses and Safety 3. Specimen Collection and Other Pre-Analytical Variables II. ANALYTICAL TECHNIQUES AND INSTRUMENTATION 4. Optical Techniques 5. Electrochemistry and Chemical Sensors 6. Electrophoresis 7. Chromatography 8. Mass Spectrometry 9. Principles of Clinical Enzymology 10. Principles of Immunochemical Techniques 11. Automation in the Clinical Laboratory 12. Point-of-Care Testing III. LABORATORY OPERATIONS 13. Selection and Analytical Evaluation of Methods - With Statistical Techniques 14. Establishment and Use of Reference Values 15. Clinical Laboratory Informatics 16. Quality Management IV. ANALYTES 17. Nucleic Acids 18. Amino Acids and Proteins 19. Enzymes 20. Tumor Markers 21. Creatinine, Uric acid, and Urea 22. Carbohydrates 23. Lipids, Lipoproteins, and Cardiac Risk Factors 24. Electrolytes and Blood Gases 25. Hormones 26. Catecholamines and Serotonin 27. Vitamins and Trace Elements 28. Hemoglobin, Iron, and Bilirubin 29. Porphyrins and Disorders of Porphyrin Metabolism 30. Therapeutic Drugs 31. Clinical Toxicology 32. Toxic Metals V. PATHOPHYSIOLOGY 33. Cardiovascular Disease 34. Renal Disease 35. Disorders of Water, Electrolyte, and Acid-Base Metabolism 36. Liver Disease 37. Gastric, Pancreatic, and Intestinal Diseases 38. Disorders of Bone 39. Pituitary Disorders 40. Adrenal Cortical Disorders 41. Thyroid Disorders 42. Reproductive Disorders 43. Disorders of Pregnancy 44. Newborn Screening VI. REFERENCE INFORMATION 45. Reference Information for the Clinical Laboratory Appendix: Review Questions Glossary
