...probably the most informative, carefully thought-out and well-written book on the subject ... invaluable not only to the undergraduate and postgraduate level students for whom it is written, but also for the chromatin community at large. In a fast-growing and ever-expanding field such as the field of chromatin research, such a book will be a rich source of reference for years to come. J Zlatanova, Heredity (2002) 89, 401
Chromatin and Gene Regulation offers a concise yet intellectually critical introduction to ... gene regulation. Science, April 2003
[The] gentle progression through the many levels of gene regulation makes this difficult subject easy to understand. The book can easily be read cover to cover, while the clear chapter layout allows students to dip in at any point. This book is ideal for students and researchers wishing to learn more about this rapidly developing subject. Lindsay Emerson, University of Essex, Newsletter of the British Society for Cell Biology, Summer 2003
Bryan M. Turner is Professor of Experimental Genetics at School of Cancer Sciences, Institute of Biomedical Research, University of Birmingham in Birmingham, UK.
He was educated at University College London, where he earned his BSc in Biochemistry and PhD in Human Biochemical Genetics.
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1. Controlling transcription: shared aims and common mechanisms.
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2. Transcription in eukaryotes: the problems of complexity.
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3. The nucleosome: chromatin's structural unit.
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4. Histone tails: modifications and epigenetic information.
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5. Higher-order chromatin structures and nuclear organisation.
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6. Transcription in a chromatin environment.
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7. How the transcription machinery deals with chromatin.
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8. Chromatin remodelling machines.
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9. Heterochromatin.
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10. Long-term silencing of gene expression.
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11. Cellular memory and imprinting.
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12. Mechanisms of dosage compensation