This handbook is designed to be a toolbox of quickly accessible clinical resources for the psychologist working in primary care settings. The Handbook will help codify the newly established role of the primary care psychologist by providing clinicians with background knowledge of the primary care system, orienting frameworks for practice, overviews of clinical conditions that are: (1) common in the primary care environment (e.g. diabetes, low back pain, sleep disorders); (2) likely to be referred to the primary care psychologist (e.g. depression, anxiety, eating disorders, grief); and, (3) treatable with well established psychological interventions (e.g. smoking, obesity, heart disease). This will be an invaluable resource to any mental health professional working as part of a health care team, as well as to researchers and students in a variety of settings.