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Part 1 An overview of biochemistry and energy considerations: an overview of biochemistry; thermodynamics in biochemistry. Part 2 Structure and function of major components of the cell: the building blocks of proteins - amino acids, peptides and polypeptides; the three-dimensional structure of proteins; functional diversity of proteins; carbohydrates, glycoproteins and cell walls; lipids and membrane structures. Part 3 Catalysis: enzyme kinetics; mechanisms of enzyme catalysis; regulatory enzymes; vitamins, coenzymes and metal cofactors. Part 4 Catabolism and the generation of chemical energy: metabolic strategies; glycolysis, gluconeogenesis and the pentose phosphate pathway; the tricarboxylic acid cycle; electron transport and the production of ATP; photosynthesis of complex carbohydrates; metabolism of phospholipids, sphingolipids and eicosanoids; cholesterol and related derivatives; integration of metabolism and hormone action. Part 6 Storage and utilization of genetic information: structures of nucleic acids and nucleoproteins; DNA replication, repair snd recombination; DNA manipulation and its applications, RNA synthesis and processing; protein synthesis and processing; regulation of gene expression in prokaryotes; regulation of gene expression in eukaryotes; mechanisms of membrane transport; immunobiology; carcinogenesis; neurotransmission; vision; glossary; answers to odd numbered problems; appendices.