In this issue of Foot and Ankle Clinics, guest editor Dr. Don Anderson brings his considerable expertise to the topic of Applied Translational Research in Foot and Ankle Surgery. Applied translational research is designed to ensure the highest possible chance of success, and in this issue, top experts in foot and ankle surgery help you produce more meaningful, applicable results that take both safety and efficacy into consideration. Contains 14 practice-oriented topics including utilizing novel in-clinic assessments to identify aberrant foot biomechanics; foot and ankle alignment and biomechanical implications; patient-specific FE analysis of foot and ankle biomechanics; biomechanics of chronic ankle instability; and more. Provides in-depth clinical reviews on applied translational research in foot and ankle surgery, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.