Large Animal Internal Medicine, 4th Edition features a problem-based approach with discussions of over 150 clinical signs. This is the first internal medicine reference that enables you to efficiently diagnose horses, cattle, sheep, and goats based on clinical observation and laboratory and diagnostic testing. With this user-friendly format, you can find essential information about specific diseases and reach a diagnosis by simply identifying the signs. Discussions of over 150 clinical signs or manifestations of disease provide you with a problem-based approach to diagnosis based on what you observe and what laboratory tests reveal. More than 200 expert authors contribute information in their areas of expertise for the most current, authoritative information on each topic. Color plates accompanying Diseases of the Eye and Diseases of the Alimentary Tract chapters illustrate the clinical appearance of ophthalmologic conditions and endoscopic views of equine alimentary tract disorders. Causes of Presenting Signs boxes offer quick access to the common, less common, and uncommon diseases associated with manifestations or signs of disease. Causes of Abnormal Laboratory Values boxes highlight the possible interpretations of abnormalities in clinical chemistry, hematology, blood proteins, and clotting tests. An extensive list of useful references on a companion website, many linked to their original source on PubMed, enables you to continue research on specific topics of interest. Thorough and extensive index makes it easy to quickly locate key information. NEW! Extensively updated content from expert authors clarifies the latest research and clinical findings on pain, the nervous system, toxicology, BVD, malignant catarrhal fever, bluetongue, and strong ions. NEW! Vaccines and vaccination protocols keep you up-to-date with the information you need to prevent newly emerging diseases in large animals. NEW! Expanded coverage of the veterinarian's role in animal welfare; equine abdominal ultrasound; DNA, genetic, and PCR testing; and colostrum supplements and replacers supplies you with the most current large animal internal medicine information. NEW! Current information on foreign animal diseases dangerous to large animals in the US, including coverage of rinderpest, keeps you aware of diseases that can be transmitted from other countries.