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Mechanisms of Protein Folding Roger H. Pain (Professor of Physical Biochemistry, Department of Biochemistry and Genetics, University of Newcastle upon Tyne)

Mechanisms of Protein Folding von Roger H. Pain (Professor of Physical Biochemistry, Department of Biochemistry and Genetics, University of Newcastle upon Tyne)

Zusammenfassung

Although scientists are aware that proteins and enzymes consist of strings of amino acids, they are still trying to discover how the one-dimensional string folds into a 3D structure that functions biologically. This account of their search explores its industrial and medical importance.

Mechanisms of Protein Folding Zusammenfassung

Mechanisms of Protein Folding Roger H. Pain (Professor of Physical Biochemistry, Department of Biochemistry and Genetics, University of Newcastle upon Tyne)

The past five years have seen a giant leap forward in our understanding of the way proteins fold into their three dimensional, functional conformations. In this volume a group of leading scientists in the field review and assess the experimental evidence that underpins these advances and look for signs of a general picture of how proteins fold. They show how these major conformational changes are leading to new insights into other fields such as membrane translocation and pore formation as well as the clinically important aggregation phenomena. A valuable handbook which will be essential for all fascinated by the power and flexibilty of proteins.

Mechanisms of Protein Folding Bewertungen

The different view and experimental approaches in the chapters should stimulate the protein chemist to search for new ideas and experiments for elucidating the folding phenomenon and approaching to optimale folding models. * D.K. Schwenke, Nahrung 40 (1996) *

Inhaltsverzeichnis

(i) The protein folding problem ; (ii) The early stages of folding ; (iii) The contribution of the molten globule model ; (iv) Proline isomerization as a rate-limiting step ; (v) The formation of native disulfide bonds ; (vi) ; (vii) Assembly of multi-subunit structures ; (viii) How the protein folds in the cell ; (ix) Protein folding in biotechnology

Zusätzliche Informationen

GOR002797642
9780199633975
0199633975
Mechanisms of Protein Folding Roger H. Pain (Professor of Physical Biochemistry, Department of Biochemistry and Genetics, University of Newcastle upon Tyne)
Gebraucht - Sehr Gut
Broschiert
Oxford University Press
1994-04-07
288
N/A
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