This book constitutes the refereed proceedings of the First International Conference on Human Factors in Computing and Informatics, SouthCHI 2013, held in Maribor, Slovenia, in July 2013. SouthCHI is the successor of the USAB Conference series and promotes all aspects of human-computer interaction. The 38 revised full papers presented together with 12 short papers, 4 posters and 3 doctoral thesis papers were carefully reviewed and selected from 169 submissions. The papers are organized in the following topical sections: measurement and usability evaluation; usability evaluation - medical environments; accessibility methodologies; game-based methodologies; Web-based systems and attribution research; virtual environments; design culture for ageing well: designing for situated elderliness; input devices; adaptive systems and intelligent agents; and assessing the state of HCI research and practice in South-Eastern Europe.