Chapter 1 Ion Channels - Physical Structures and Gating Mechanisms Chapter 2 Mitochondrial Membrane Channels - Physical Structures and Gating Mechanisms Chapter 3 Ion Channels of the Nuclear Membrane - Physical Structures and Gating Mechanisms Chapter 4 Artificial Ion Channels Chapter 5 Nonchannel Membrane Gating Chapter 6 Ion Channel Energetics Chapter 7 Nanotechnology of Ion Channels Chapter 8 Channelopathies and Ion Channels as Therapeutic Targets Chapter 9 Bioinformatics of Ion channels: Artificial Intelligence, Machine Learning, and Deep Learning Chapter 10 Quantum Mechanics of Ion Channels