This latest edition of The Cytotoxics Handbook has been extensively updated and expanded. It now includes the effective employment of drug agents in combination, leading to improved clinical outcomes in a variety of conditions. Following the continuing concern of healthcare workers, guidelines on the toxicity of drugs are identified and include the latest evidence and best practice. For added benefit, the author of each monograph is identified and can be consulted on specific queries. The Fourth Edition retains the existing popular structure, with, part one dealing with the operation of cytotoxic services while part two is a compendium of monographs on each chemotherapeutic agent, biological and adjuvant therapy. It is an essential reference tool for all hospital pharmacists and technicians, as well as nurses and clinicians treating cancer, pharmaceutical companies and cancer research institutes.