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Antiviral Nucleosides C.K. Chu (College of Pharmacy, University of Georgia, Athens, GA, USA)

Antiviral Nucleosides By C.K. Chu (College of Pharmacy, University of Georgia, Athens, GA, USA)

Antiviral Nucleosides by C.K. Chu (College of Pharmacy, University of Georgia, Athens, GA, USA)


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Summary

Presents a review on the chemistry and biology of nucleosides. This book summarizes the advances in nucleosides chemistry and chemotherapy. It covers nucleoside antiviral agents, their therapeutic aspects and biochemistry, and also reviews on their chiral synthesis.

Antiviral Nucleosides Summary

Antiviral Nucleosides: Chiral Synthesis and Chemotherapy by C.K. Chu (College of Pharmacy, University of Georgia, Athens, GA, USA)

* Up-to-date review on the chemistry and biology of nucleosides* Modern synthetic methodology* Comprehensive coverage of antiviral nucleosidesThis book summarizes the recent advances in nucleosides chemistry and chemotherapy over the past 10-15 years. It covers recently discovered nucleoside antiviral agents, their therapeutic aspects and biochemistry, and also extensive reviews on their chiral synthesis.

Table of Contents

1. Recent Advances in Antiviral Nucleosides. (G. Gumina, Y. Choi, C.K. Chu). Introduction. Structural features of nucleosides as antiviral agents. 2'-Deoxy nucleosides and related analogs. 2',3'-Dideoxy nucleosides and related analogues. 2',3'-Unsaturated nucleosides and related analogues. Nucleosides with a heterocyclic sugar ring moiety. 3- or 4-Membered ring nucleosides. Acyclonucleosides. Ribofuranosyl nucleosides. References. 2. Chiral synthesis of antiviral nucleosides from carbohydrate templates. (G. Gumina, S. Olgen, C.K. Chu). Introduction. 4'-Thiofuranose nucleosides. Iso- and apio nucleosides. Oxathiolane and dioxolane nucleosides. Cyclopentyl carbocyclic nucleosides. Cyclopropyl carbocyclic nucleosides. C-Nucleosides. Fluorinated nucleosides. Acyclonucleosides. Miscellaneous nucleosides. References. 3. Oxathiolane and dioxolane nucleosides: Synthesis and antiviral activity. (G. Gumina, J.S. Cooperwood, C.K. Chu). Introduction. Oxathiolane nucleosides. Synthesis. Antiviral activity. Combination therapy. Dioxolane nucleosides. Synthesis. Antiviral activity. References.

Additional information

NPB9780444513199
9780444513199
0444513191
Antiviral Nucleosides: Chiral Synthesis and Chemotherapy by C.K. Chu (College of Pharmacy, University of Georgia, Athens, GA, USA)
New
Hardback
Elsevier Science & Technology
2003-10-15
268
N/A
Book picture is for illustrative purposes only, actual binding, cover or edition may vary.
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