A medical miracle has occurred. Dr. Pavlov has successfully performed his 'behaviour control' techniques on the first human subject, Cruella De Vil, the fur-wearing puppy napper who ended up in the slammer. The world's sneakiest, surliest, most flamboyant villainess is transformed from fashion diva into compassionate animal lover and renamed Ella. But there's a flaw in Pavlov's Plan. A loud noise at a particular frequency breaks the conditioning and when Big Ben's thunderous chimes reach her ears it's bye bye Ella. Cruella's back!