In the east end of Regency London, two families lie butchered. Residents of the notorious Ratcliffe Highway, the victims bear the mark of unprecedented brutality.

Panic sweeps the country as its public cries for justice. But these murders stem from an older horror, its source a sea voyage two centuries old. In a ship owned by Queen Elizabeth herself, a young man embarks on England's first venture into a new trade: human souls.

As a nation's sins ripen and bloom, to be harvested in a bloody frenzy on the twisted streets of Regency Wapping, an English Monster is born.