Chapter 1 Maximal Safe Resection in Glioblastoma: Use of Adjuncts (Daria Krivosheya, Marcos Vinicius Calfatt Maldaun and Sujit S Prabhu). - Chapter 2 Molecular Pathology of Glioblastoma- an Update (Vani Santosh, Palavalasa Sravya and Arimappamagan Arivazhagan).- Chapter 3 Current Therapies and Future Directions in Treatment of Glioblastoma (Joshua L. Wang, Luke Mugge, Pierre Giglio and Vinay Puduvalli).- Chapter 4 Recent Advances for Targeted Therapies in Glioblastoma (Michael Youssef, Jacob Mandel, Sajeel Chowdhary, and Santosh Kesari).- Chapter 5 Targeting EGFR in Glioblastoma: Molecular Biology and Current Understanding (Sepulveda JM, Zahonero C, Sanchez-Gomez P).- Chapter 6 Radiogenomics & Histomics in Glioblastoma - The Promise of Linking Image-derived Phenotype with Genomic Information (Michael Lehrer, Reid T. Powell, Souptik Barua, Donnie Kim, Shivali Narang, and Arvind Rao).- Chapter 7 Next-generation Sequencing in Glioblastoma Personalized Therapy (Jagriti Pal, Vikas Patil and Kumaravel Somasundaram).- Chapter 8 Glioma Stem-like Cells in Tumor Growth and Therapy Resistance of Glioblastoma (Abhirami Visvanathan and Kumaravel Somasundaram).- Chapter 9 Animal Models in Glioblastoma: Use in Biology and Developing Therapeutic Strategies (Schuhmacher A.J. and Squatrito M).- Chapter 10 Pediatric High Grade Glioma (Chitra Sarkar, Suvendu Purkait, Pankaj Pathak and Prerana Jha).