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DAVID SADAVA, Claremont Colleges, USA is the Pritzker Family Foundation Professor of Biology, Emeritus, at the Keck Science Center of Claremont McKenna, Pitzer, and Scripps, three of The Claremont Colleges. In addition, he is Adjunct Professor of Cancer Cell Biology at the City of Hope Medical Center. Twice winner of the Huntoon Award for superior teaching, Dr. Sadava taught courses on introductory biology, biotechnology, biochemistry, cell biology, molecular biology, plant biology, and cancer biology. For the past 15 years, he has investigated multi-drug resistance in human small-cell lung carcinoma cells with a view to understanding and overcoming this clinical challenge, and his current work focuses on new anti-cancer agents from plants and fungi. DAVID HILLIS, University of Texas, USA is the Alfred W. Roark Centennial Professor in Integrative Biology and the Director of the Center for Computational Biology and Bioinformatics at the University of Texas at Austin, where he also has directed the School of Biological Sciences. He has taught courses in introductory biology, genetics, evolution, systematics, and biodiversity. His research interests span much of evolutionary biology, including experimental studies of evolving viruses, empirical studies of natural molecular evolution, applications of phylogenetics, analyses of biodiversity, and evolutionary modeling. He is particularly interested in teaching and research about the practical applications of evolutionary biology. H. CRAIG HELLER, Stanford University, USA is the Lorry I. Lokey/Business Wire Professor in Biological Sciences and Human Biology at Stanford University. He is a recipient of the Walter J. Gores Award for excellence in teaching. His research is on the neurobiology of sleep and circadian rhythms, mammalian hibernation, the regulation of body temperature, the physiology of human performance, and the neurobiology of learning. Dr. Heller has done research on a huge variety of animals and physiological problems ranging from sleeping kangaroo rats, diving seals, hibernating bears, photoperiodic hamsters, and exercising athletes. MAY BERENBAUM, University of Illinois, USA is the Swanlund Professor and Head of the Department of Entomology at the University of Illinois at Urbana-Champaign. She has taught courses in introductory animal biology, entomology, insect ecology, and chemical ecology and has received awards at the regional and national level for distinguished teaching from the Entomological Society of America. Her research addresses insect-plant co-evolution from molecular mechanisms of detoxification to impacts of herbivory on community structure. Concerned with the practical application of ecological and evolutionary principles, she has examined impacts of genetic engineering, global climate change, and invasive species on natural and agricultural ecosystems.

PART I: THE SCIENCE OF LIFE AND ITS CHEMICAL BASIS 1. Studying Life 2. Small Molecules and the Chemistry of Life 3. Proteins, Carbohydrates, and Lipids 4. Nucleic Acids and the Origin of Life PART II: CELLS 5. Cells: The Working Units of Life 6. Cell Membranes 7. Cell Communication and Multicellularity PART III: CELLS AND ENERGY 8. Energy, Enzymes, and Metabolism 9. Pathways that Harvest Chemical Energy 10. Photosynthesis: Energy from Sunlight PART IV: GENES AND HEREDITY 11. The Cell Cycle and Cell Division 12. Inheritance, Genes, and Chromosomes 13. DNA and Its Role in Heredity 14. From DNA to Protein: Gene Expression 15. Gene Mutation and Molecular Medicine 16. Regulation of Gene Expression PART V: GENOMES 17. Genomes 18. Recombinant DNA and Biotechnology 19. Differential Gene Expression in Development 20. Development and Evolutionary Change PART VI: THE PATTERNS AND PROCESSES OF EVOLUTION 21. Mechanisms of Evolution 22. Reconstructing and Using Phylogenies 23. Speciation 24. Evolution of Genes and Genomes 25. The History of Life on Earth PART VII: THE EVOLUTION OF DIVERSITY 26. Bacteria, Archaea, and Viruses 27. The Origin and Diversification of Eukaryotes 28. Plants without Seeds: From Water to Land 29. The Evolution of Seed Plants 30. The Evolution and Diversity of Fungi 31. Animal Origins and the Evolution of Body Plans 32. Protostome Animals 33. Deuterostome Animals PART VIII: FLOWERING PLANTS: FORM AND FUNCTION 34. The Plant Body 35. Transport in Plants 36. Plant Nutrition 37. Regulation of Plant Growth 38. Reproduction in Flowering Plants 39. Plant Responses to Environmental Challenges PART IX: ANIMALS: FORM AND FUNCTION 40. Physiology, Homeostasis, and Temperature Regulation 41. Animal Hormones 42. Immunology: Animal Defense Systems 43. Animal Reproduction 44. Animal Development: From Genes to Organisms 45. Neurons, Glia, and Nervous Systems 46. Sensory Systems 47. The Mammalian Nervous System 48. Musculoskeletal Systems 49. Gas Exchange 50. Circulatory Systems 51. Nutrition, Digestion, and Absorption 52. Salt and Water Balance and Nitrogen Excretion 53. Animal Behavior PART X: ECOLOGY 54. Ecology and the Distribution of Life 55. Population Ecology 56. Species Interactions and Coevolution 57. Community Ecology 58. Ecosystems and Global Ecology 59. Biodiversity and Conservation Biology