The brain is crucial for the regulation of whole-body metabolism and behavior. The pancreas-derived hormone insulin modulates brain function and affects energy metabolism as well as cognition.
Prof. Dr. Andre Kleinridders is Professor for Experimental and Molecular Nutritional Medicine at the Institute of Nutritional Science at the University of Potsdam, Germany. Dr. Kleinridders' research program aims at understanding causes and consequences of brain insulin resistance with implications for diabetes, obesity and neurological disorders. His studies focus on in the interaction of mitochondrial function and insulin signaling and its consequences on energy homeostasis and behavior. Several publications establish Dr. Kleinridders' unique research focus on the role of brain insulin in metabolic disorders.
1 Molecular mechanisms of brain insulin signaling
2 Insulin/IGF signaling in early brain development
3 Insulin signaling modulates neuronal metabolism
4 Regulation of glial function by insulin peptides
5 Neuroendocrine interactions in the control of glucose- and energy homeostasis
6 Hypothalamic neuronal circuits are modulated by insulin and impact metabolism
7 Insulin and brain reward systems
8 The impact of insulin on brain serotonergic system: consequences on diabetes-associated mood disorders
9 Organ cross-talk regulates (brain) insulin action
10 Insulin resistance as a risk factor for Alzheimer's disease
11 Brain insulin action in the control of metabolism in humans
12 Impact of dietary and exercise interventions on brain insulin action and brain function
13 Pharmacological and surgical interventions to improve brain insulin resistance