Andrew Mitchell, Consultant Cardiologist, Jersey General Hospital, Jersey, Channel Islands, and Honorary Consultant Cardiologist, John Radcliffe Hospital, Oxford, UK, Nick West, Consultant Cardiologist, Papworth Hospital, Cambridge, UK, Paul Leeson, Honorary Consultant Cardiologist, John RadcliffeHospital, Oxford, UK and BHF Clinical Science Fellow, University of Oxford, Oxford, UK, Adrian Banning, Consultant Cardiologist, John Radcliffe Hospital, Oxford, UK