This story of madness reveals the radically different perceptions of madness and approaches to its treatment, from antiquity to the beginning of the 21st century. Roy Porter explores what we really mean by "madness", covering an enormous range of topics from witches to creative geniuses, electric shock therapy to sexual deviancy, and psychoanalysis to Prozac. The origins of debates about how we define and deal with insanity are examined through eyewitness accounts of those treating patients, writers, artists, and the mad themselves.