This is a core textbook for medical students that integrates basic science and clinical immunology. The book has been written by two co-authors experienced in teaching integrated immunology courses, giving it a cohesiveness lacking in multi-author texts. In addition, the text has been extensively reviewed by subject specialists to ensure its authority. The focus is on the human immunology required by students to understand and treat common immunological diseases, animal research is included only where essential for an understanding of the subject. Designed to convey this complex subject easily, the book makes extensive use of key point and clinical boxes and is illustrated throughout with two-colour graphics.