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The current epidemic of obesity; overweight, mortality, and morbidity; the cost of obesity and sedentarism in the United Sates; the determinants of obesity; assessment of human energy expenditure; the assessment of energy and nutrient intake in humans; human energy and nutrient balance; adipose tissue metabolism and obesity; skeletal muscle metabolism and obesity; physical activity and body composition in children and adolescents; physical activity level and weight control in adults; physical activity and weight control in older citizens; physical activity and prevention and treatment of weight gain associated with pregnancy; physical activity level and the treatment of severe obesity; physical activity and maintenance of weight loss - physiological and psychological mechanism; physical activity and the metabolic complications of obesity; is it possible to be overweight or obese and fit and healthy?; changing lifestyle - moving from sedentary to active.