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Microarray Methods for Drug Discovery Sridar V. Chittur

Microarray Methods for Drug Discovery By Sridar V. Chittur

Microarray Methods for Drug Discovery by Sridar V. Chittur

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Microarray Methods for Drug Discovery Summary

Microarray Methods for Drug Discovery by Sridar V. Chittur

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Microarray Methods for Drug Discovery Reviews

From the reviews:

"Microarray Methods for Drug Discovery is volume number 632 of the Springer Protocols Methods in Biology Series. ... it provides detailed experimental protocols for the use of microarrays in a variety of applications. ... chapters are obviously highly bespoke and would be of real value to laboratories wishing to establish the method. Finally, the microarray area is now so broad that the non-nucleic acid application of microarrays would justify a methods book in its own right." (James Sidaway, BTS Newsletter, Issue 37, Winter, 2010)

"Methods in Microarrays provide scientists with a complete resource on the most effective tools available for maximizing microarray data in biochemical methods. ... Microarrays are extensively used in the effects of compounds on gene expression in cells. This book aims at enlightening individuals of all levels of experience about some of the most common applications of microarrays in drug discovery and development. This book will serve as a reference for students and scientists ... ." (Veni Maria Andres Felli, Brazilian Journal of Pharmaceutical Sciences, May, 2010)

Table of Contents

1. Multicenter Clinical Sample Collection for Microarray Analysis Tony S. Mondala, Daniel R. Salomon, and Steven R. Head 2. Selective Isolation of Total RNA from Mouse Melanoma Subsets Using Fluorescence Activated Cell Sorting Scott Tighe and Matthew A. Held 3. Microarray Analysis of Embryonic Stem Cells and Differentiated Embryoid Bodies Alexander C. Zambon and Christopher S. Barker 4. Determination of Alternate Splicing Events Using the Affymetrix Exon 1.0 ST Arrays Sita Subbaram, Marcy Kuentzel, David Frank, C. Michael DiPersio, and Sridar V. Chittur 5. Profiling microRNA Expression with the Illumina BeadChip Platform Julissa Tsao, Patrick Yau, and Neil Winegarden 6. TaqMan (R) Array Cards in Pharmaceutical Research David N. Keys, Janice K. Au-Young, and Richard A. Fekete 7. DMET (TM) Microarray Technology for Pharmacogenomics-Based Personalized Medicine James K. Burmester, Marina Sedova, Michael H. Shapero, and Elaine Mansfield 8. The Use of Microarray Technology for Cytogenetics Bassem A. Bejjani, Lisa G. Shaffer, and Blake C. Ballif 9. PCR/LDR/Universal Array Platforms for the Diagnosis of Infectious Disease Maneesh Pingle, Mark Rundell, Sanchita Das, Linnie M. Golightly, and Francis Barany 10. RIP-CHIP in Drug Development Ritu Jain, Francis Doyle, Ajish D. George, Marcy Kuentzel, David Frank, Sridar V. Chittur, and Scott A. Tenenbaum 11. ChIPing Away At Global Transcriptional Regulation Kelly Jackson, James Paris, and Mark Takahashi 12. HELP (HpaII Tiny Fragment Enrichment by Ligation-Mediated PCR) Assay for DNA Methylation Profiling of Primary Normal and Malignant B Lymphocytes Rita Shaknovich, Maria E. Figueroa, and Ari Melnick 13. High-Throughput Screening of Metalloproteases Using SmallMolecule Microarrays Mahesh Uttamchandani 14. Metabolic Enzyme Microarray Coupled with Miniaturized Cell-Culture Array Technology for High-Throughput Toxicity Screening Moo-Yeal Lee, Jonathan S. Dordick, and Douglas S. Clark 15. Use of Tissue Microarray to Facilitate Oncology Research Panagiotis Gouveris, Paul M. Weinberger, and Amanda Psyrri 16. Small Molecule Selectivity and Specificity Profiling Using Functional Protein Microarrays Peter R. Kraus, Lihao Meng, and Lisa Freeman-Cook 17. Production and Application of Glycan Microarrays Julia Busch, Ryan McBride, and Steven R. Head

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Microarray Methods for Drug Discovery by Sridar V. Chittur
Humana Press Inc.
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