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Design and Analysis of DNA Microarray Investigations Richard M. Simon

Design and Analysis of DNA Microarray Investigations By Richard M. Simon

Design and Analysis of DNA Microarray Investigations by Richard M. Simon


$26.49
Condition - Very Good
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Summary

The analysis of gene expression profile data from DNA micorarray studies are discussed in this book. It includes an Appendix tutorial on the use of BRB-ArrayTools and step by step analyses of several major datasets using this software which is available from the National Cancer Institute.

Design and Analysis of DNA Microarray Investigations Summary

Design and Analysis of DNA Microarray Investigations by Richard M. Simon

The analysis of gene expression profile data from DNA micorarray studies are discussed in this book. It provides a review of available methods and presents it in a manner that is intelligible to biologists. It offers an understanding of the design and analysis of experiments utilizing microarrays to benefit scientists. It includes an Appendix tutorial on the use of BRB-ArrayTools and step by step analyses of several major datasets using this software which is available from the National Cancer Institute.

Design and Analysis of DNA Microarray Investigations Reviews

From the reviews:

This book gives a welcome introduction to microarray data and its analysis. Such analyses have been performed for many years, but only recently are new investigators able to read about the topic in such a concise and well-written format. Journal of Biopharmaceutical Statistics, Issue #4, 2005

I enjoyed it and recommend it for anyone working in this area. Short Book Reviews of the ISI, April 2005

This is a book to get your biological collaborators to read, because it provides good statistical perspectives on the design of experiments and on other methodologies needed to design and analyze microarray experiments. The treatment is straightforward, but not simple. Journal of the American Statistical Association, June 2005

The book presents the basics of microarray technology and follows with chapters on designing experiments and processing the scanned images. Further to this, it provides an introduction to selecting appropriate analysis techniques that will result in valid answers. ... The understanding of many of the statistical applications is enhanced by the inclusion of several real-world medical datasets as examples. (Rebecca E. Walls)

A very good overview of the issues and techniques, suitable for a non-specialist readership that would be interested to embark on microarray studies. Throughout, the authors discuss both spotted cDNA arrays and oligonucleotide arrays ... which adds further merit to this book. ... A great asset of this book is that all the example data are freely available for analysis ... . an excellent introduction to all aspects of microarray analyses ... a very good read ... . (Dirk - Jan De Koning, Genetical Research, Vol. 84, 2004)

This book presents a concise overview of many useful statistical approaches to microarray data ... . This broad range of topics makes the book unique and useful. ... this book is a valuable resource for microarray experimenters. I enjoyed it and recommend it for anyone working in this area. (R. Tibshirani, Short Book Reviews, Vol. 25(1), 2005)

This book is concerned with methods of analyzing data obtained from DNA microarray experiments. ... The book is written for biologists without a strong statistical background, and also for computer scientists and statisticians interested in being collaborators in studies utilizing microarrays. (Alexander Mitrophanov, Zentralblatt MATH, Vol. 1039(8), 2004)

The small number of noisy microarrays relative to the large number of genes presents a challenge to biologists using this technology. This book aims to aid the biologist in solving some of these problems ... . It largely achieves this aim. ... the chapters are logically integrated and perfectly consistent with each other. ... describes, overall, a sensible approach to microarray analysis. ... the authors have done an excellent job in presenting sensible statistical methodology to the biological community. (Ernst Wit, Human Genetics, Vol. 1(6), November

For the biomedical researcher, it promises an introduction and survey to the principles of biometrical thinking ... . For the biometrician, it describes typical experimental approaches, data structures, design and analysis problems ... . We are convinced that this book is a must for all readers who are interested in the design, conduct and analysis of microarray gene expression experiments. It will certainly impact on the necessary communication between researchers of all type engaged in this truly cross disciplinary subject. (Dirk Repsilber and Andreas Ziegler, Metrika, Vol. 64, 2006)

Analysis of data arising from microarray experiments is one of the very exciting areas in statistics these days. ... it is important to have text books that can serve the dual purpose of catering basic biology related to microarray experiments to statisticians and exposing to biologists the basic statistical techniques needed for designing microarray experiments and analyzing data generated from such experiments. ... This book will be quite useful for biostatisticians and biologists interested in microarray experiments and related data analysis. (Probal Chaudhuri, Sankhya, Vol. 67 (1), 2005)

Microarray experiments are rapidly growing in popularity for their ability to analyze DNA samples with relative ease. This book, penned by a collection of current and former members of the Biometric Research Branch at the National Cancer Institute, offers a concise yet comprehensive guide to designing and analyzing such experiments. ... The book is aimed at biologists with limited statistical knowledge ... . (Journal of Applied Statistics, Vol. 32 (4), 2005)

Table of Contents

Introduction * DNA Microarray Technology * Design of DNA Microarray Experiments * Image Analysis * Quality Control * Array Normalization * Class Comparison * Class Prediction * Class Discovery

Additional information

GOR012388360
9780387001357
0387001352
Design and Analysis of DNA Microarray Investigations by Richard M. Simon
Used - Very Good
Hardback
Springer-Verlag New York Inc.
20040108
200
N/A
Book picture is for illustrative purposes only, actual binding, cover or edition may vary.
This is a used book - there is no escaping the fact it has been read by someone else and it will show signs of wear and previous use. Overall we expect it to be in very good condition, but if you are not entirely satisfied please get in touch with us

Customer Reviews - Design and Analysis of DNA Microarray Investigations