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Immunoinformatics By Rajat K. De

Immunoinformatics by Rajat K. De

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Summary

At the intersection of experimental and computational sciences, the second edition of Immunoinformatics provides biological insights as well as a simpler way to implement approaches and algorithms in the immunoinformatics research domain.

Immunoinformatics Summary

Immunoinformatics by Rajat K. De

At the intersection of experimental and computational sciences, the second edition of Immunoinformatics provides biological insights as well as a simpler way to implement approaches and algorithms in the immunoinformatics research domain. After an introductory section, this extensive volume moves on to cover topics such as databases, tools for prediction, systems biology approaches, as well as a variety of immunoinformatics applications. As part of the highly successful Methods in Molecular Biology series, chapters include the type of detailed information and implementation advice to ensure successful results.

Comprehensive and practical, Immunoinformatics, Second Edition aims at students and researchers from diverse backgrounds and levels interested in working with immunological problems.

Table of Contents

Part I: Immunoinformatics: Transition from Basic Biology to Informatics

1. A Brief Outline of the Immune System

Namrata Tomar and Rajat K. De

2. Crosstalk Between the Metabolic and Immune Systems

Namrata Tomar and Rajat K. De

3. Immunoinformatics: A Brief Review

Namrata Tomar and Rajat K. De

Part II: Databases

4. Immunoinformatics of the V, C and G Domains: IMGT (R) Definitive System for IG, TR and IgSF, MH and MhSF

Marie-Paule Lefranc

5. IMGT/HLA and the Immuno Polymorphism Database

James Robinson, Jason A. Halliwell, and Steven G.E. Marsh

6. Databases for T-Cell Epitopes

Chun-Wei Tung

7. Databases for B-Cell Epitopes

Juan Liu and Wen Zhang

8. Antigen-Antibody Interaction Database (AgAbDb): A Compendium of Antigen-Antibody Interactions

Urmila Kulkarni-Kale, Snehal Raskar-Renuse, Girija Natekar-Kalantre, and Smita A. Saxena

9. Allergen Databases

Gaurab Sircar, Debasree Sarkar, Swati Gupta Bhattacharya, and Sudipto Saha

Part III: Tools for Prediction

10. Prediction of Conformational B-Cell Epitopes

Wen Zhang, Yanqing Niu, Yi Xiong, and Meng Ke

11. Computational Prediction of B Cell Epitopes from Antigen Sequences

Jianzhao Gao and Lukasz Kurgan

12. Machine Learning Based Methods for Prediction of Linear B-Cell Epitopes

Hsin-Wei Wang and Tun-Wen Pai

13. Mimotope-Based Prediction of B-Cell Epitopes

Jian Huang and Peng Zhou

14. Hybrid Methods for B-Cell Epitope Prediction: Approaches to the Development and Utilization of Computational Tools for Practical Applications

Salvador Eugenio C. Caoili

15. Building Hybrid Classifiers for B-Cell Epitopes Prediction

Yasser EL-Manzalawy and Vasant Honavar

16. Multiplex Peptide-Based B-Cell Epitope Mapping

Sanne M.M. Hensen, Merel Derksen, and Ger J.M. Pruijn

17. Classification of Human Leukocyte Antigen (HLA) Supertypes

Mingjun Wang and Mogens H. Claesson

18. Customized Predictions of Peptide-MHC Binding and T-Cell Epitopes Using EPIMHC

Magdalena Molero-Abraham, Esther M. Lafuente, and Pedro Reche

19. T-Cell Epitope Prediction Methods: An Overview

Dattatraya V. Desai and Urmila Kulkarni-Kale

20. Computational Antigenic Epitope Prediction by Calculating Electrostatic Desolvation Penalties of Protein Surfaces

Sebastien Fiorucci and Martin Zacharias

21. In Silico Prediction of Allergenic Proteins

Gaurab Sircar, Bodhisattwa Saha, Swati Gupta Bhattacharya, and Sudipto Saha

22. Prediction of Virulence Factors Using Bioinformatics Approaches

Rupanjali Chaudhuri and Srinivasan Ramachandran

Part IV: Systems Biology Approaches in Immunoinformatics

23. A Systems Biology Approach to Study Systemic Inflammation

Bor-Sen Chen and Chia-Chou Wu

24. Procedures for Mucosal Immunization and Analyses of Cellular Immune Response to Candidate HIV Vaccines in Murine and Nonhuman Primate Models

Shailbala Singh, Pramod Nehete, Patrick Hanley, Bharti Nehete, Guojun Yang, Hong He, Scott M. Anthony, Kimberly Schluns, and K. Jagannadha Sastry

25. Immunoinformatics and Systems Biology in Personalized Medicine

Guillermo Lopez-Campos, Jesus F. Bermejo-Martin, Raquel Almansa, and Fernando Martin-Sanchez

Part V: Applications of Immunoinformatics

26. The Role of Small RNAs in Vaccination

Ajeet Chaudhary and Sunil Kumar Mukherjee

27. Structure-Based Clustering of Major Histocompatibility Complex (MHC) Proteins for Broad-Based T-Cell Vaccine Design

Joo Chuan Tong, Tin Wee Tan, and Shoba Ranganathan

28. Immunoinformatics, Molecular Modeling, and Cancer Vaccines

Seema Mishra and Subrata Sinha

29. Investigating Host Pathogen Behavior and Their Interaction Using Genome-Scale Metabolic Network Models

Priyanka P. Sadhukhan and Anu Raghunathan

30. Mathematical Models of HIV Replication and Pathogenesis

Dominik Wodarz

Additional information

NPB9781493911141
9781493911141
1493911147
Immunoinformatics by Rajat K. De
New
Hardback
Humana Press Inc.
2014-07-22
586
N/A
Book picture is for illustrative purposes only, actual binding, cover or edition may vary.
This is a new book - be the first to read this copy. With untouched pages and a perfect binding, your brand new copy is ready to be opened for the first time

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