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Hemostasis and Thrombosis By Emmanuel J. Favaloro

Hemostasis and Thrombosis by Emmanuel J. Favaloro

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Hemostasis and Thrombosis Summary

Hemostasis and Thrombosis: Methods and Protocols by Emmanuel J. Favaloro

This collection thoroughly explores the dynamic and ever-developing field of hemostasis and thrombosis diagnostics and research. After an introductory section covering the basics and preanalytical issues, the book continues with in-depth sections that explore how to get the best outcomes from routine coagulation and specialized hemostasis assays, thrombophilia-related techniques, investigations into bleeding disorders, as well as performance of global assays of hemostasis, and finally post-analytical issues in hemostasis and thrombosis testing. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Comprehensive and practical, Hemostasis and Thrombosis: Methods and Protocols serves as an ideal resource for researchers and diagnostic laboratories seeking expert guidance and working to identify the best methodologies to pursue hemostasis and thrombosis testing.

Table of Contents

Part I: Introductory Chapters

1. Overview of Hemostasis and Thrombosis and Contribution of Laboratory Testing to Diagnosis and Management of Hemostasis and Thrombosis Disorders

Roslyn A. Bonar, Giuseppe Lippi, and Emmanuel J. Favaloro

2. Preanalytical Issues in Hemostasis and Thrombosis Testing

Giuseppe Lippi and Emmanuel J. Favaloro

3. The Interface between Immunotransfusion and Hemostasis and Thrombosis Testing

Massimo Franchini

Part II: Routine Coagulation Assays

4. Optimizing the Verification of Mean Normal Prothrombin Time (MNPT) and International Sensitivity Index (ISI) for Accurate Conversion of Prothrombin Time (PT) to International Normalized Ratio (INR)

Emmanuel J. Favaloro

5. Performance of Activated Partial Thromboplastin Time (APTT): Determining Reagent Sensitivity to Factor Deficiencies, Heparin, and Lupus Anticoagulants

Geoffrey Kershaw

6. Performance and Interpretation of Mixing Tests in Coagulation

Geoffrey Kershaw

7. D-Dimer Testing: Laboratory Aspects and Current Issues

Jecko Thachil, Giuseppe Lippi, and Emmanuel J. Favaloro

8. Determination of Fibrinogen and Thrombin Time (TT)

Anetta Undas

Part III: Thrombophilia-Related Chapters

9. An Overview of Thrombophilia and Associated Laboratory Testing

Martina Montagnana, Giuseppe Lippi, and Elisa Danese

10. Laboratory Testing for Activated Protein C Resistance (APCR)

Soma Mohammed and Emmanuel J. Favaloro

11. Assessment of Hereditary Thrombophilia: Performance of Protein C (PC) Testing

Richard A. Marlar and Jana N. Gausman

12. Assessment of Hereditary Thrombophilia: Performance of Protein S (PS) Testing

Richard A. Marlar and Jana N. Gausman

13. Assessment of Hereditary Thrombophilia: Performance of Antithrombin (AT) Testing

Jana N. Gausman and Richard A. Marlar

14. Lupus Anticoagulant Testing: Diluted Russell Viper Venom Time (dRVVT)

Vittorio Pengo, Elisa Bison, Alessandra Banzato, Giacomo Zoppellaro, Seena Padayattil Jose, and Gentian Denas

15. Lupus Anticoagulant Testing: Activated Partial Thromboplastin Time (APTT) and Silica Clotting Time (SCT)

Armando Tripodi and Veena Chantarangkul

16. Solid Phase Immunoassay for the Detection of Anticardiolipin Antibodies

Rohan Willis, Elizabeth Papalardo, and E. Nigel Harris

17. Solid Phase Immunoassay for the Detection of Anti- 2 Glycoprotein I Antibodies

Rohan Willis, Elizabeth Papalardo, and E. Nigel Harris

18. Measuring Direct Oral Anticoagulants

Robert C. Gosselin and Jonathan Douxfils

19. Laboratory Testing Protocols for Heparin-Induced Thrombocytopenia (HIT) Testing

Kun Kan Edwin Lau, Soma Mohammed, Leonardo Pasalic, and Emmanuel J. Favaloro

Part IV: Bleeding Disorders

20. One-Stage Factor VIII Assays

Elizabeth Duncan and Susan Rodgers

21. Chromogenic Factor VIII Assays for Improved Diagnosis of Hemophilia A

Susan Rodgers and Elizabeth Duncan

22. Assessment of Factor XIII

Laszlo Muszbek, Eva Katona, and Adrienne Kerenyi

23. Detection and Measurement of Factor Inhibitors

Geoffrey Kershaw

24. Platelet Function Tests: Preanalytical Variables, Clinical Utility, Advantages and Disadvantages

Anne-Mette Hvas and Erik Lerkevang Grove

25. Platelet Function Analyzed by Light Transmission Aggregometry

Anne-Mette Hvas and Emmanuel J. Favaloro

26. Whole Blood Platelet Aggregometry

George A. Fritsma and David L. McGlasson

27. Assessment of Platelet Function in Whole Blood by Flow Cytometry

Leonardo Pasalic

28. Flow Cytometry Protocols for Assessment of Platelet Function in Whole Blood

Leonardo Pasalic, Gabrielle J. Pennings, David Connor, Heather Campbell, Leonard Kritharides, and Vivien M. Chen

29. Diagnosis or Exclusion of Von Willebrand Disease Using Laboratory Testing

Emmanuel J. Favaloro

30. Laboratory Testing for Von Willebrand Factor Antigen (VWF:Ag)

Emmanuel J. Favaloro, Soma Mohammed, and Jurgen Patzke

31. Laboratory Testing for Von Willebrand Factor Collagen Binding (VWF:CB)

Emmanuel J. Favaloro and Soma Mohammed

32. Laboratory Testing for Von Willebrand Factor Ristocetin Cofactor (VWF:RCo)

Soma Mohammed and Emmanuel J. Favaloro

33. Laboratory Testing for Von Willebrand Factor Activity by Glycoprotein Ib Binding Assays (VWF:GPIb)

Jurgen Patzke and Emmanuel J. Favaloro

34. Laboratory Testing for Von Willebrand Factor Factor VIII Binding (for 2N VWD)

Soma Mohammed and Emmanuel J. Favaloro

35. Ristocetin-Induced Platelet Aggregation (RIPA) and RIPA Mixing Studies

Juan Pablo Frontroth and Emmanuel J. Favaloro

36. Laboratory Testing for Von Willebrand Factor Multimers

Susan Oliver, Kun Kan Edwin Lau, Kent Chapman, and Emmanuel J. Favaloro

Part V: Global Assays and Post-Analytical Issues

37. Thrombin Generation Assays (TGA)

Gian Luca Salvagno and Erik Berntorp


38. The Overall Haemostatic Potential (OHP) Assay

Jennifer Curnow

39. Thromboelastography (TEG)

Maha Othman and Harmanpreet Kaur

40. Post-Analytical Issues in Hemostasis and Thrombosis Testing

Emmanuel J. Favaloro and Giuseppe Lippi

Additional information

NPB9781493971947
9781493971947
1493971948
Hemostasis and Thrombosis: Methods and Protocols by Emmanuel J. Favaloro
New
Hardback
Humana Press Inc.
2017-08-14
565
N/A
Book picture is for illustrative purposes only, actual binding, cover or edition may vary.
This is a new book - be the first to read this copy. With untouched pages and a perfect binding, your brand new copy is ready to be opened for the first time

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