The many dramatic moments of Secretary Hillary Clinton's tenure as Secretary of State frame her thoughts about the recent history of US foreign policy and the urgent, on-going need for American leadership in a changing world. In this truly global work, Hillary Clinton writes about her role in, and reflects on, such critical events as the killing of Osama Bin Laden, the overthrow of the Qaddafi regime in Libya, the transitions in Iraq and Afghanistan, the Arab Spring, the pivot to the Asia-Pacific, the rise of new powers such as China, Brazil, Turkey and India, the building of diplomatic coalitions to deal with Iran and North Korea, and America's relations with important allies around the world. Secretary Clinton also addresses many of the major trends reshaping the global landscape of the 21st century including trends in economics, energy and climate change, democracy and human rights, the critical role of women and girls, technology and innovation, and health and human development. Throughout, Secretary Clinton offers vivid personal anecdotes and memories of her collaboration with President Obama and his National Security team, as well as her engagement with leaders around the world.